
The Quintus engine is a simple HTML5 game engine designed to be modular and lightweight, with a concise JavaScript-friendly syntax.
Colbalt Calibur 3 is an real-time-ish multi-player MMO that uses Canvas and Node.js. It's open source duel licensed under the BSD/GPL.
DivSugar is a CSS3 based 3D graphics engine. While it's not as performant as a WebGL might be for full games, the fact that it uses CSS3 means that it can easily be integrated into existing sites and be used for casual games.
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